United States securities and exchange commission logo March 20, 2023 Jeffrey Mathiesen Chief Financial Officer HELIUS MEDICAL TECHNOLOGIES, INC. 642 Newton Yardley Road, Suite 100 Newton, Pennsylvania 18940 Re: HELIUS MEDICAL TECHNOLOGIES, INC. Registration Statement on Form S-3 Filed March 10, 2023 File No. 333-270433 Dear Jeffrey Mathiesen: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Jessica Ansart at 202-551-4511 with any questions. Sincerely, Division of Corporation Finance Office of Industrial Applications and Services cc: Emily J. Johns