United States securities and exchange commission logo April 23, 2024 Dane C. Andreeff Chief Executive Officer Helius Medical Technologies, Inc. 642 Newtown Yardley Road, Suite 100 Newtown, Pennsylvania 18940 Re: Helius Medical Technologies, Inc. Registration Statement on Form S-1 Filed April 15, 2024 File No. 333-278698 Dear Dane C. Andreeff: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Benjamin Richie at 202-551-7857 with any questions. Sincerely, Division of Corporation Finance Office of Industrial Applications and Services cc: Emily Johns