United States securities and exchange commission logo September 22, 2020 Dane C. Andreeff Interim President and Chief Executive Officer Helius Medical Technologies, Inc. 642 Newtown Yardley Road, Suite 100 Newtown, PA 18940 Re: Helius Medical Technologies, Inc. Registration Statement on Form S-1 Filed September 15, 2020 File No. 333-248824 Dear Mr. Andreeff: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Deanna Virginio at 202-551-4530 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Meredith Ervine, Esq.