United States securities and exchange commission logo December 2, 2020 Dane Andreeff Interim President and Chief Executive Officer Helius Medical Technologies, Inc. 642 Newtown Yardley Road, Suite 100 Newtown, Pennsylvania 18940 Re: Helius Medical Technologies, Inc. Registration Statement on Form S-1 Filed November 25, 2020 File No. 333-250974 Dear Mr. Andreeff: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Courtney Lindsay at (202) 551-7237 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences