United States securities and exchange commission logo September 10, 2021 Dane Andreeff President and Chief Executive Officer HELIUS MEDICAL TECHNOLOGIES, INC. 642 Newtown Yardley Road, Suite 100 Newtown, Pennsylvania 18940 Re: HELIUS MEDICAL TECHNOLOGIES, INC. Registration Statement on Form S-1 Filed September 3, 2021 File No. 333-259334 Dear Dane Andreeff: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Michael Davis at 202-551-4385 or Laura Crotty at 202-551-7614 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Phillip D. Torrence